Using Glandular Therapies

Health Tips / Using Glandular Therapies

Given the comments on our blog following last week’s post on glandular therapies, let me say first that if you’re a vegetarian or vegan, glandular therapies are definitely not for you. But if you’re a veggie or vegan needing digestive enzymes, there are plenty of plant-based products. You’ll also face no compromise if you need thyroid (Synthroid), adrenal (Cortef), or ovary (birth control pills) hormones. Synthetic versions are readily available for these, as well as for others I’ll review today.

Using the glands or other organs of animals for medicinal treatment, also called organotherapy, goes back to ancient medical times, part of the timeless phenomenon known as “like heals like.” Cultural anthropologists have been encountering this phrase, along with “as above, so below,” quite literally since the dawn of man. Contemporary Western physicians tend not to think too much about these old medical tenets, dismissing them as too arcane to be of any use today even as they routinely prescribe these well-known “like cure like” treatments:

• Flu shots and other immunizations.

• Allergy shots.

• Hormones to prevent pregnancy or hot flashes.

• Hormones to support thyroid or adrenal glands.

Interesting, isn’t it, that in each of these like is literally curing like—the flu vaccine giving you a tiny bit of inactivated flu virus, allergy shots delivering a miniscule amount of what you’re allergic to, and tiny doses of hormones providing what may be missing from your body. How tiny? Birth control pills are currently dosed in micrograms. If you didn’t know, a microgram is one-millionth of a gram.

As a rule, doctors are far more comfortable prescribing synthetic versions of everything.

By the final decades of the 20th century, the development of synthetic hormones brought research using animal-based glandulars to a halt. Yet clinicians did agree that certain animal gland and organ preparations, when taken orally, were quite effective in treating a variety of conditions. What makes these treatments effective? There are probably two reasons. First, and this is especially in the case of glands like the thyroid and adrenals, the glandular is replacing missing hormone. But second, and this is where “like cures like” comes in, the complex molecules of the gland or organ in the supplement provide the precise building blocks necessary for repair or restoration. What better source for the missing components of, for example, a damaged liver than concentrated liver?

Virtually all animal-derived products used medicinally today originate from organically fed livestock that live outdoors and receive no chemicals or antibiotics. The most common method of extracting active ingredients is by immediately freeze-drying the gland or organ to 60 degrees below zero and then placing it into a vacuum chamber to remove water and concentrate the active ingredients.

In addition to integrative doctors like me, naturopathic physicians prescribe glandulars quite frequently. But since most of the 5,000 naturopaths in the US can’t obtain a license in Illinois, Midwesterners are generally unfamiliar with using a naturopath as a primary caregiver. The National University of the Health Sciences in suburban Chicago offers a degree in naturopathic medicine, but in order to practice in Illinois graduates must also hold a “licensable” degree like chiropractic. Virtually all graduates of the other certified naturopathic colleges in North America practice outside our state.

Glandular products and conditions they treat

Since so many glands and organs are used in naturopathic medicine, I’ll list the better-known products and the conditions they treat. If you’re prone to doing your own research, you’ll find clinical studies in conventional medical journals on most of these. Those marked with an * are currently stocked in our apothecary. The others can be ordered and generally arrive in a few days.

Adrenal cortex extract*

Chronic fatigue, asthma, eczema, psoriasis.

Aorta (the largest artery of the cardiovascular system) extracts
Blood vessel diseases: stroke, arteriosclerosis, varicose veins, hemorrhoids.

Bone marrow extracts

Various anemias.

Brain extracts*

Various dementias and stroke damage. Occasionally as part of an anti-aging protocol.

Heart extract

Chronic heart disease of all types.


Exhaustion of the hypothalamic-pituitary-adrenal (HPA) stress responding circuit, when it’s best used with adrenal cortex extract. Chronic fatigue.

Kidney extract

Chronic kidney diseases of all types.

Liver extract

Chronic liver diseases, including chronic hepatitis.

Lung extract

Chronic bronchitis and emphysema; asthma.

Lymph gland (often combined with thymus gland)

Weak immune system; frequent colds and flu.

Orchic (testicle)*

Male infertility; low sex drive in men.


Female infertility; low sex drive in women.


Poor digestion. Very high doses used for some cancers.


Prevention and/or treatment of prostate disorders.

Spleen extract

Immune enhancement. Autoimmune disorders such as lupus, rheumatoid arthritis, ulcerative colitis, and celiac disease.


Chronic or recurring viral infections. Chronic fatigue syndrome.

Thyroid (prescription only)
Underactive thyroid.

How to use glandular therapy

You might now be wondering “Is this all for me to decide myself, as a do-it-myself doctor? Am I supposed to start taking bits of brain or ovary or hypothalamus without any guidance?” No. But I’m of two minds about this.

On the one hand, when it comes to making your own diagnosis (with the exception of something relatively minor, like a cold or bladder infection), you, like most people, will likely get your diagnosis wrong, regardless the hours invested on the internet. Medical diagnosis is non-syllogistic and this can be highly confusing for people looking up their symptoms on the web. Here’s an example:


The most common syllogism:
All men are mortal.
Socrates is a man.
Therefore: Socrates is a mortal.


The non-syllogism of medicine:
Brain tumors cause headaches.
I have a headache.
Therefore: I have a brain tumor.


Understand that medical doctors, osteopaths, chiropractors, and naturopaths spend years studying this stuff and are simply better at determining what’s wrong with you. So if you have chronic symptoms that concern you, please get a proper diagnosis before you start ordering products and swallowing things or trying any therapy–conventional, alternative, nutritional, glandular, herbal, energy, or otherwise.

On the other hand, remember the proactive patient always (always!) does better than the passive-acceptant one. When it comes to healthcare, feistiness and taking charge of your well-being is a virtue. A big part of being proactive is to first understand your properly diagnosed condition and then to explore alternative therapies. For example, if you’re diagnosed with chronic hepatitis and research glandular therapy for it, you’d find studies showing benefits to taking liver extract for this condition.

You could then show this research to your hepatologist (liver doc), who’s probably never heard of using extracts and, rather than bothering to learn something new, would likely discourage it, claiming they might interfere with what really works (his opinion of the drug he’s prescribing). In this case, you really would need advice from an integrative physician, whose expertise encompasses both pharmaceuticals and glandulars.

Be well,

David Edelberg, MD

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    Posted May 15, 2023 at 6:31 am

    I’m dealing with hypothyroidism and lowered adrenal function. I’ve been taking thyroid glandular and adrenal cortex glandular for several months. I’ve been under the impression by Dr. that these glandulars just feed and nourish the glands back to health. So I’m concerned now.. Will the glandulars cause my thyroid and adrenals to “shut down” if I stay on them for more than several months?

    J. Ramer
    Posted January 6, 2021 at 1:17 pm

      Hi there

      Generally, glandulars can reduce the effectiveness of your glands very slightly over time. Best to make the decision to start and stay on glandular therapies.

      Posted January 11, 2021 at 1:11 am

      Hi, I used thyroid and liver glandular off and on for a few years, and I haven’t had any problems being off them for probably five years or more now. I did support my system in other ways during that time though so I never planned to stay on them. Once I started feeling better, I swapped to nutritional support and detoxing. I now have no thyroid or adrenal issues and ell normal for the first time in my life, I’m 47.

      Posted March 7, 2022 at 1:11 pm

    I was told by my naturopath as well as my fertility screening ( low LH) that I have issues with my HPA axis. Should I be taking just pituitary gland or should I take ovary as well?

    Lisa A Richardson
    Posted December 12, 2020 at 12:14 am

      Hi Lisa,
      This is definitely a question for your naturopath; it depends a lot on where the problem in the axis exists, and how severe it is. If you’d like a second opinion, any of our functional medicine practitioners would be happy to help you with this. You can schedule a telemedicine visit or in-person consultation to go over everything and decide your next steps. Our scheduling staff can be reached at 773-296-6700.

      Posted December 13, 2020 at 11:58 pm

    Saw your comment about glandulars with kidney disease. My husband, is in fact, working with a doctor in his use of a kidney glandular for his kidney disease. We are at least hoping it will stall the worsening of the disease. The doctor is studying what he can. And we have to decide if he should take it more than once a day.

    Posted July 18, 2020 at 2:38 pm

    What is the recommended dose of orchic enzyme per day?

    Posted June 16, 2018 at 5:03 pm

      Hi Ivan. It depends upon what you’re treating but without specific clinical information, we’d recommend that you follow the dosage on the bottle.

      Dr. R
      Posted June 17, 2018 at 11:30 am

    Hi Paul
    This should not occur as dose is very low

    Dr E
    Posted May 28, 2018 at 1:07 pm

    Would you experience mild shut down of the HPTA axis while using orchic glandular ?

    Posted May 26, 2018 at 1:01 pm

    What are the thoughts of taking a kidney glandular to treat kidney disease. Kidney disease seems to indicate that the kidney can’t be repaired and once it’s damaged there’s no turning back (right?). Would it be a waste, in this case, to take a glandular if a damaged kidney can’t be repaired?

    Greg Wilkinson
    Posted September 3, 2017 at 10:46 am

      Greg. Kidney disease can be very serious; please consult with your PCP and/or a nephrologist. A glandular supplement will probably not be very helpful.

      Dr. R
      Posted September 4, 2017 at 10:51 am

    I have been wondering if glandulars are used directly meaning if you have weak kidneys you take kidney glandular OR more of an indirect route, for example if your pituitary isnt working, would you take pituitary or hypothalamus? Thanks!

    Denise Chapman
    Posted August 21, 2017 at 12:23 am

      Glandulars are used both directly and indirectly according to a patient’s unique picture. When using glandulars, it’s best to do so with the help of a health care provider who can make customized recommendations based on your health picture and follow you as you use them. At WHC, any of our physicians or Nurse Practitioners can help with this.

      Dr M

      Posted August 21, 2017 at 4:37 am

    Hi Kyle
    That’s an excellent question. We can extrapolate the effect of thyroid glandular on the thyroid and adrenal glandular on the adrenal. In these cases, there is a minimal temporary suppression that reverses a few days after the glandular is stopped and the function of the gland returns to pre-treatment levels.
    Since glandulars were abandoned by conventional medicine decades ago, the only current research you might find would be in naturopathic journals.

    Dr E
    Posted June 18, 2016 at 4:54 pm

    Thanks for the article. What is your opinion on the notion that glandulars are dangerous because they cause the organ or gland to atrophy or shut down its own production of hormones and endogenous compounds? Is there any possibility of this, and for which glandular if so? What sear h terms would one look for in the journals whe b researchING this? Organo therapy?

    Posted June 17, 2016 at 11:36 pm

    Hi Eric
    Generally lung glandulars are used for more acute situations (bronchitis, pneumonia, etc.) and I am unfamiliar with any work being done for a complex condition like cystic fibrosis. That said, using lung glandulars would be a completely harmless therapy and may be helpful. There are several suppliers and this one seems reliable. Scroll down until you reach “Simply Lung”

    Dr E
    Posted September 12, 2015 at 4:26 pm

    Are lung glandulars something you might expect to help with cystic fibrosis conditions?

    Posted September 11, 2015 at 10:29 pm

    Why are Standard Process supplements discouraged. A chiropractor in another state uses these all the time.

    Vivian Hood
    Posted January 15, 2013 at 9:49 pm

      Standard Process uses synthetic forms of some of their vitamins, and their filler ingredients are even worse than their synthetic vitamins. There are much better supplement companies on the market such as Biotics Research and OrthoMolecular.

      Posted October 15, 2019 at 11:21 am

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